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Ultimate Sweet-and-Sour Beef Brisket

Ultimate Sweet-and-Sour Beef Brisket pairs rich, slow-cooked beef with a tangy-sweet glaze of ketchup, vinegar, and brown sugar that melts into tender slices. Onion and garlic deepen the flavor, creating a comforting balance of brightness and richness. It’s perfect for a family dinner, holiday table, or any gathering where you want a hearty, crowd-pleasing main.

  • Prep15 mins
  • Cook2 hrs 45 mins
  • Serves10
  • DifficultyMedium
Ultimate Sweet-and-Sour Beef Brisket
  1. 1

    In a large skillet or Dutch oven over medium-high heat, sear the brisket until browned on all sides. Add the water, ketchup, vinegar, onions, garlic, brown sugar, and salt, and stir. Bring to a boil, then cover and lower the heat to medium-low. Simmer until tender, turning the brisket occasionally, 2 hours and 30 minutes to 3 hours and 30 minutes.

  2. 2

    Take out the brisket and let it cool, then slice the meat against the grain. Arrange the brisket slices in a 9x13-inch baking pan or on a large platter and pour the gravy over the top. Cover and refrigerate overnight. Remove any excess fat and reheat before serving.