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Ladybug's Poppy Seed Chicken Casserole

Ladybug's Poppy Seed Chicken Casserole layers tender chunks of chicken in a rich, tangy sauce under a buttery cracker crust studded with nutty poppy seeds. It bakes up golden with a toasty crunch on top and a cozy, velvety center—perfect for weeknight dinners or sharing at potlucks when you want something nostalgic and satisfying.

  • Prep15 mins
  • Cook1 hr
  • Serves8
  • DifficultyEasy
Ladybug's Poppy Seed Chicken Casserole
  1. 1

    Preheat the oven to 350 degrees F (175 degrees C).

  2. 2

    Combine the cracker crumbs, melted butter, and poppy seeds in a bowl. Spread 2/3 of the cracker mixture over the bottom of a 9x13-inch glass baking dish. Stir the chicken breast pieces with the cream of chicken soup and sour cream until well mixed, then spoon this mixture over the crumb layer. Sprinkle the remaining 1/3 of the cracker mixture over the top of the chicken mixture.

  3. 3

    Bake in the preheated oven until the casserole is hot and bubbling, about 1 hour.